{"id":12912,"date":"2025-01-07T04:26:13","date_gmt":"2025-01-07T04:26:13","guid":{"rendered":"https:\/\/www.info-welt.com\/en\/index.php\/2025\/01\/07\/breakthrough-hereditary-deafness-treatment-in-mice\/"},"modified":"2025-01-07T04:26:13","modified_gmt":"2025-01-07T04:26:13","slug":"breakthrough-hereditary-deafness-treatment-in-mice","status":"publish","type":"post","link":"https:\/\/www.info-welt.com\/en\/index.php\/2025\/01\/07\/breakthrough-hereditary-deafness-treatment-in-mice\/","title":{"rendered":"Breakthrough: Hereditary Deafness Treatment in Mice"},"content":{"rendered":"<p>Scientists at Mass Eye and Ear have made a breakthrough in treating genetic <b>hearing loss<\/b>. They\\&#8217;ve discovered that over 50% of children with <b>hearing loss<\/b> have a single genetic abnormality<sup class=\\\"citation\\\"><a href=\\\"https:\/\/www.nih.gov\/news-events\/nih-research-matters\/genome-editing-restores-hearing-mice\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">1<\/a><\/sup>. Their study focuses on developing targeted treatments using advanced gene editing techniques<sup class=\\\"citation\\\"><a href=\\\"https:\/\/www.theguardian.com\/science\/2017\/dec\/20\/breakthrough-for-genetic-hearing-loss-as-gene-editing-prevents-deafness-in-mice\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">2<\/a><\/sup>.<\/p>\n<p>The team used the CRISPR-Cas9 gene editing system for treatment. They delivered it through a harmless virus injected into the inner ear<sup class=\\\"citation\\\"><a href=\\\"https:\/\/www.nih.gov\/news-events\/nih-research-matters\/genome-editing-restores-hearing-mice\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">1<\/a><\/sup>. Treated mice showed hearing improvements lasting up to nine months<sup class=\\\"citation\\\"><a href=\\\"https:\/\/www.nih.gov\/news-events\/nih-research-matters\/genome-editing-restores-hearing-mice\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">1<\/a><\/sup>.<\/p>\n<p><b>Genetic disorders<\/b> are crucial in <b>auditory research<\/b>. Nearly half of all deafness cases are due to genetic causes<sup class=\\\"citation\\\"><a href=\\\"https:\/\/www.theguardian.com\/science\/2017\/dec\/20\/breakthrough-for-genetic-hearing-loss-as-gene-editing-prevents-deafness-in-mice\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">2<\/a><\/sup>. The study showed that early treatment could greatly impact long-term hearing preservation<sup class=\\\"citation\\\"><a href=\\\"https:\/\/www.nih.gov\/news-events\/nih-research-matters\/genome-editing-restores-hearing-mice\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">1<\/a><\/sup>.<\/p>\n<h3>Key Takeaways<\/h3>\n<ul>\n<li><b>Gene therapy<\/b> offers breakthrough potential for treating hereditary <b>hearing loss<\/b><\/li>\n<li>CRISPR-Cas9 technology shows promise in restoring auditory function<\/li>\n<li>Early intervention may significantly improve hearing preservation<\/li>\n<li>Over 50% of childhood hearing loss has a genetic origin<\/li>\n<li>Innovative research bridges the gap between <b>mouse models<\/b> and human treatment<\/li>\n<\/ul>\n<h2>Understanding Hereditary Deafness in Mice<\/h2>\n<p><b>Mouse models<\/b> offer crucial insights into genetic hearing disorders. Scientists have found links between gene mutations and hearing loss. These discoveries could transform how we treat hearing problems.<\/p>\n<h3>What Causes Hereditary Deafness?<\/h3>\n<p>Hereditary deafness comes from complex genetic processes. <em>Approximately 50 percent of hearing loss cases are genetic in nature<\/em><sup class=\\\"citation\\\"><a href=\\\"https:\/\/eyeandear.org\/2022\/08\/hereditary-hearing-loss-new-innovations-for-treatment\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">3<\/a><\/sup>. Genetic hearing impairments have some key features:<\/p>\n<ul>\n<li>Over 124 non-syndromic hearing loss genes have been identified<sup class=\\\"citation\\\"><a href=\\\"https:\/\/eyeandear.org\/2022\/08\/hereditary-hearing-loss-new-innovations-for-treatment\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">3<\/a><\/sup><\/li>\n<li>Genetic mutations can impact hearing development at multiple stages<\/li>\n<li>Some mutations directly damage inner ear structures<\/li>\n<\/ul>\n<h3>Impact on Mouse Models<\/h3>\n<p><b>Mouse models<\/b> are vital for studying genetic hearing disorders. Researchers have found gene mutations in mice similar to human hearing loss<sup class=\\\"citation\\\"><a href=\\\"http:\/\/ncats.nih.gov\/news-events\/news\/with-gene-editing-mice-with-a-form-of-inherited-deafness-can-hear-again\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">4<\/a><\/sup>.<\/p>\n<p>For example, MIR96 gene mutations can cause complete high-frequency hearing loss. This happens within four weeks after birth in mice.<\/p>\n<blockquote><p>\\&#8221;Mouse research provides a critical window into understanding complex genetic hearing mechanisms\\&#8221;<\/p><\/blockquote>\n<h3>Importance of Animal Research<\/h3>\n<p>Animal research is key to developing treatments for <b>genetic disorders<\/b>. <em>Approximately 5% of the world\\&#8217;s population experiences disabling hearing loss<\/em><sup class=\\\"citation\\\"><a href=\\\"https:\/\/www.nature.com\/articles\/s41392-022-00893-4\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">5<\/a><\/sup>. This makes advanced research techniques crucial.<\/p>\n<p>Gene editing in mice has shown promise in restoring hearing. By studying genetic pathways, scientists may find new ways to treat hearing loss.<\/p>\n<h2>Recent Advances in Treatment Options<\/h2>\n<p>Hearing loss treatment is rapidly changing. New <b>gene therapy<\/b> and cellular approaches offer hope for hereditary deafness. Researchers are exploring ways to address genetic hearing issues at their core<sup class=\\\"citation\\\"><a href=\\\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10124073\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">6<\/a><\/sup>.<\/p>\n<h3>Gene Therapy Innovations<\/h3>\n<p><b>Gene therapy<\/b> is a promising new way to treat hearing loss. Scientists have found over 150 deafness genes. These genes give researchers targets for genetic treatments<sup class=\\\"citation\\\"><a href=\\\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10124073\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">6<\/a><\/sup>.<\/p>\n<p>The scientific community is making big steps in targeted treatments. These include gene replacement, gene suppression, and CRISPR-Cas9 gene editing<sup class=\\\"citation\\\"><a href=\\\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10509501\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">7<\/a><\/sup>.<\/p>\n<ul>\n<li>Gene replacement techniques to correct specific genetic mutations<\/li>\n<li>Gene suppression strategies for problematic genetic expressions<\/li>\n<li>Advanced CRISPR-Cas9 gene editing approaches<sup class=\\\"citation\\\"><a href=\\\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10509501\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">7<\/a><\/sup><\/li>\n<\/ul>\n<blockquote><p>\\&#8221;Gene therapy offers the potential to address fundamental genetic causes of hearing loss, moving beyond traditional treatment methods.\\&#8221; &#8211; <b>Regenerative Medicine<\/b> Research Team<\/p><\/blockquote>\n<h3>Cellular Therapy Approaches<\/h3>\n<p><b>Biotechnology<\/b> is changing how we treat hearing loss. About 1 in 500 babies are born with genetic hearing loss. This makes new therapies very important<sup class=\\\"citation\\\"><a href=\\\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10509501\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">7<\/a><\/sup>.<\/p>\n<p>Key cellular strategies include:<\/p>\n<ol>\n<li><em>Targeted gene editing<\/em> using CRISPR-Cas systems<\/li>\n<li>Precision cellular reconstruction techniques<\/li>\n<li>Molecular-level genetic interventions<sup class=\\\"citation\\\"><a href=\\\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10124073\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">6<\/a><\/sup><\/li>\n<\/ol>\n<p>These new treatments are not just ideas. Over 300 clinical trials are testing gene therapy for various <b>genetic disorders<\/b>. These studies could lead to repairing genetic hearing problems<sup class=\\\"citation\\\"><a href=\\\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10124073\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">6<\/a><\/sup><sup class=\\\"citation\\\"><a href=\\\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10509501\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">7<\/a><\/sup>.<\/p>\n<h2>Implications for Human Health<\/h2>\n<p><b>Molecular genetics<\/b> research offers exciting possibilities for addressing hearing loss through <b>biotechnology<\/b>. Scientists have discovered promising pathways to transform our understanding of genetic hearing disorders. <a href=\\\"https:\/\/www.nih.gov\/news-events\/nih-research-matters\/technique-treats-hereditary-deafness-mice\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">Translational research<\/a> reveals remarkable potential for future therapies<sup class=\\\"citation\\\"><a href=\\\"https:\/\/advances.massgeneral.org\/otolaryngology\/journal.aspx?id=2605\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">8<\/a><\/sup>.<\/p>\n<p>Recent scientific advances could revolutionize our understanding of genetic hearing loss. Over 150 genetic loci link to hereditary hearing loss, creating a complex research landscape<sup class=\\\"citation\\\"><a href=\\\"https:\/\/advances.massgeneral.org\/otolaryngology\/journal.aspx?id=2605\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">8<\/a><\/sup>.<\/p>\n<p>No biological treatment exists for hereditary deafness, making this research crucial<sup class=\\\"citation\\\"><a href=\\\"https:\/\/advances.massgeneral.org\/otolaryngology\/journal.aspx?id=2605\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">8<\/a><\/sup>.<\/p>\n<h3>Translational Research Benefits<\/h3>\n<p>This research\\&#8217;s potential benefits exceed initial expectations. CRISPR-Cas9 genome editing successfully treats hereditary diseases in mouse models<sup class=\\\"citation\\\"><a href=\\\"https:\/\/advances.massgeneral.org\/otolaryngology\/journal.aspx?id=2605\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">8<\/a><\/sup>.<\/p>\n<p><em>Precision gene editing<\/em> offers hope for addressing multiple genetic mutations at once<sup class=\\\"citation\\\"><a href=\\\"https:\/\/advances.massgeneral.org\/otolaryngology\/journal.aspx?id=2605\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">8<\/a><\/sup>.<\/p>\n<ul>\n<li>Potential to treat 15 genetic forms of inherited deafness<\/li>\n<li>Ability to target single-letter mutations<\/li>\n<li>Promising approach for 20% of dominantly inherited genetic diseases<\/li>\n<\/ul>\n<h3>Potential for New Therapies<\/h3>\n<p>The research suggests a new way to treat hearing loss. Scientists salvaged hearing in mouse models, showing remarkable improvements in auditory function<sup class=\\\"citation\\\"><a href=\\\"https:\/\/answers.childrenshospital.org\/crispr-hearing-loss\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">9<\/a><\/sup>.<\/p>\n<p>Beethoven mice, usually deaf by 6 months, showed near-normal hearing after gene-editing therapy<sup class=\\\"citation\\\"><a href=\\\"https:\/\/answers.childrenshospital.org\/crispr-hearing-loss\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">9<\/a><\/sup>.<\/p>\n<blockquote><p>The future of genetic hearing loss treatment looks promising, with groundbreaking techniques offering hope for millions affected by hereditary deafness.<\/p><\/blockquote>\n<p>Our understanding of genetic hearing loss keeps evolving. This approach could identify thousands of defective gene variants<sup class=\\\"citation\\\"><a href=\\\"https:\/\/answers.childrenshospital.org\/crispr-hearing-loss\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">9<\/a><\/sup>.<\/p>\n<p>It potentially opens new frontiers in <b>biotechnology<\/b> and <b>translational research<\/b><sup class=\\\"citation\\\"><a href=\\\"https:\/\/answers.childrenshospital.org\/crispr-hearing-loss\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">9<\/a><\/sup>.<\/p>\n<h2>Future Directions in Research<\/h2>\n<p><b>Auditory research<\/b> is evolving rapidly. Innovative approaches in <b>regenerative medicine<\/b> offer groundbreaking solutions for hearing loss. Researchers are expanding gene therapy techniques to transform treatment for genetic hearing disorders<sup class=\\\"citation\\\"><a href=\\\"https:\/\/hsci.harvard.edu\/news\/gene-therapy-restores-hearing-deaf-mice-down-whisper\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">10<\/a><\/sup>.<\/p>\n<p>These developments could lead to crucial medical breakthroughs. Your understanding of this progress is important for future advancements.<\/p>\n<h3>Upcoming Studies in Mice<\/h3>\n<p>Biotechnology studies will explore genetic interventions in mouse models. Scientists aim to develop new therapies for over 100 genes causing deafness<sup class=\\\"citation\\\"><a href=\\\"https:\/\/hsci.harvard.edu\/news\/gene-therapy-restores-hearing-deaf-mice-down-whisper\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">10<\/a><\/sup>.<\/p>\n<p>The research will focus on improving gene delivery methods. It will also look at extending treatment windows for hearing restoration<sup class=\\\"citation\\\"><a href=\\\"https:\/\/www.nature.com\/articles\/s41467-018-08264-w\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">11<\/a><\/sup>.<\/p>\n<h3>Collaborations with Biomedical Companies<\/h3>\n<p>Partnerships between academia and biomedical companies are speeding up hearing loss treatment progress. <a href=\\\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10265000\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">Boston Children\\&#8217;s Hospital researchers are pioneering<\/a> gene therapy for hearing restoration<sup class=\\\"citation\\\"><a href=\\\"https:\/\/hsci.harvard.edu\/news\/gene-therapy-restores-hearing-deaf-mice-down-whisper\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">10<\/a><\/sup>.<\/p>\n<p>These collaborations turn lab findings into clinical applications. They could help the 466 million people worldwide affected by hearing challenges<sup class=\\\"citation\\\"><a href=\\\"https:\/\/www.nature.com\/articles\/s41467-018-08264-w\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">11<\/a><\/sup>.<\/p>\n<p>The future of <b>auditory research<\/b> is bright. Teams are working hard to unlock new therapeutic possibilities. Your support can help drive these scientific advances forward.<\/p>\n<section class=\\\"schema-section\\\">\n<h2>FAQ<\/h2>\n<div>\n<h3>What is the breakthrough in treating hereditary deafness in mice?<\/h3>\n<div>\n<div>\n<p>Scientists at Mass Eye and Ear in Boston made a groundbreaking discovery. They used CRISPR-Cas9 to restore hearing in adult mice. This method targeted the MIR96 gene mutation, improving hair cell survival and hearing.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<h3>How does the MIR96 gene mutation affect hearing in mice?<\/h3>\n<div>\n<div>\n<p>The MIR96 gene mutation causes hair cell loss in mice. It leads to complete high-frequency hearing loss four weeks after birth. This condition mimics human DFNA50, making mice ideal for studying genetic hearing loss.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<h3>What gene therapy approaches are being explored for hereditary deafness?<\/h3>\n<div>\n<div>\n<p>Scientists are exploring various gene therapy strategies. These include gene editing, replacement, suppression, and cellular therapies. CRISPR-Cas9 shows promise in targeting specific mutations with a single injection.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<h3>Why are mouse models important in hearing loss research?<\/h3>\n<div>\n<div>\n<p>Mouse models help test interventions at different stages. They allow close study of genetic hearing loss mechanisms. These models bridge lab research and potential human treatments, paving the way for clinical trials.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<h3>What makes the inner ear suitable for gene therapy?<\/h3>\n<div>\n<div>\n<p>The inner ear\\&#8217;s confined structure is ideal for gene therapy. Its compact nature allows therapeutic agents to reach target cells efficiently. This increases the potential for successful genetic interventions.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<h3>What are the implications of this research for human hearing loss?<\/h3>\n<div>\n<div>\n<p>The successful treatment in adult mice offers hope for humans. It opens up possibilities for treating various forms of inherited deafness. However, more preclinical studies are needed before human trials can begin.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<h3>What are the future research directions for treating hereditary deafness?<\/h3>\n<div>\n<div>\n<p>Future research will focus on improving gene therapy delivery methods. Scientists aim to enhance long-term outcomes and treat more genetic mutations. Collaborations between researchers and biomedical companies will speed up therapy development.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<h2>Source Links<\/h2>\n<ol data-type=\\\"sources\\\">\n<li>Genome editing restores hearing in mice &#8211; <a href=\\\"https:\/\/www.nih.gov\/news-events\/nih-research-matters\/genome-editing-restores-hearing-mice\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">https:\/\/www.nih.gov\/news-events\/nih-research-matters\/genome-editing-restores-hearing-mice<\/a><\/li>\n<li>Breakthrough for genetic hearing loss as gene editing prevents deafness in mice &#8211; <a href=\\\"https:\/\/www.theguardian.com\/science\/2017\/dec\/20\/breakthrough-for-genetic-hearing-loss-as-gene-editing-prevents-deafness-in-mice\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">https:\/\/www.theguardian.com\/science\/2017\/dec\/20\/breakthrough-for-genetic-hearing-loss-as-gene-editing-prevents-deafness-in-mice<\/a><\/li>\n<li>Hereditary Hearing Loss: New Innovations for Treatment &#8211; Eye &amp; Ear Foundation of Pittsburgh &#8211; <a href=\\\"https:\/\/eyeandear.org\/2022\/08\/hereditary-hearing-loss-new-innovations-for-treatment\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">https:\/\/eyeandear.org\/2022\/08\/hereditary-hearing-loss-new-innovations-for-treatment\/<\/a><\/li>\n<li>With Gene Editing, Mice with a Form of Inherited Deafness Can Hear Again &#8211; <a href=\\\"http:\/\/ncats.nih.gov\/news-events\/news\/with-gene-editing-mice-with-a-form-of-inherited-deafness-can-hear-again\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">http:\/\/ncats.nih.gov\/news-events\/news\/with-gene-editing-mice-with-a-form-of-inherited-deafness-can-hear-again<\/a><\/li>\n<li>Preventing autosomal-dominant hearing loss in Bth mice with CRISPR\/CasRx-based RNA editing &#8211; Signal Transduction and Targeted Therapy &#8211; <a href=\\\"https:\/\/www.nature.com\/articles\/s41392-022-00893-4\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">https:\/\/www.nature.com\/articles\/s41392-022-00893-4<\/a><\/li>\n<li>Advances in gene therapy hold promise for treating hereditary hearing loss &#8211; <a href=\\\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10124073\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10124073\/<\/a><\/li>\n<li>Recent advances in CRISPR-Cas system for the treatment of genetic hearing loss &#8211; <a href=\\\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10509501\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10509501\/<\/a><\/li>\n<li>CRISPR-Cas9 Genome Editing Treats Genetic Hearing Loss &#8211; <a href=\\\"https:\/\/advances.massgeneral.org\/otolaryngology\/journal.aspx?id=2605\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">https:\/\/advances.massgeneral.org\/otolaryngology\/journal.aspx?id=2605<\/a><\/li>\n<li>Precision CRISPR system averts hearing loss in mice &#8211; Boston Children\\&#8217;s Answers &#8211; <a href=\\\"https:\/\/answers.childrenshospital.org\/crispr-hearing-loss\/\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">https:\/\/answers.childrenshospital.org\/crispr-hearing-loss\/<\/a><\/li>\n<li>Gene therapy restores hearing in deaf mice&#8230; down to a whisper &#8211; <a href=\\\"https:\/\/hsci.harvard.edu\/news\/gene-therapy-restores-hearing-deaf-mice-down-whisper\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">https:\/\/hsci.harvard.edu\/news\/gene-therapy-restores-hearing-deaf-mice-down-whisper<\/a><\/li>\n<li>Improved\u00a0TMC1 gene therapy restores hearing and balance in mice with genetic inner ear disorders &#8211; Nature Communications &#8211; <a href=\\\"https:\/\/www.nature.com\/articles\/s41467-018-08264-w\\\" target=\\\"_blank\\\" rel=\\\"nofollow\\\">https:\/\/www.nature.com\/articles\/s41467-018-08264-w<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Discover groundbreaking research on Hereditary Deafness Treatment in Mice that offers new hope for genetic hearing loss. Learn how scientists are making strides in gene therapy<\/p>\n","protected":false},"author":1,"featured_media":12913,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[5],"tags":[383,384,385,386,387],"class_list":["post-12912","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","tag-genetic-research","tag-hearing-loss-treatment","tag-hereditary-deafness","tag-inner-ear-regeneration","tag-mice-models"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"wpmanag984","author_link":"https:\/\/www.info-welt.com\/en\/author\/wpmanag984\/"},"uagb_comment_info":0,"uagb_excerpt":"Discover groundbreaking research on Hereditary Deafness Treatment in Mice that offers new hope for genetic hearing loss. Learn how scientists are making strides in gene therapy","_links":{"self":[{"href":"https:\/\/www.info-welt.com\/en\/index.php\/wp-json\/wp\/v2\/posts\/12912","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.info-welt.com\/en\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.info-welt.com\/en\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.info-welt.com\/en\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.info-welt.com\/en\/index.php\/wp-json\/wp\/v2\/comments?post=12912"}],"version-history":[{"count":0,"href":"https:\/\/www.info-welt.com\/en\/index.php\/wp-json\/wp\/v2\/posts\/12912\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.info-welt.com\/en\/index.php\/wp-json\/wp\/v2\/media?parent=12912"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.info-welt.com\/en\/index.php\/wp-json\/wp\/v2\/categories?post=12912"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.info-welt.com\/en\/index.php\/wp-json\/wp\/v2\/tags?post=12912"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}